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Table 2 Results of ATMP transport validation in dry ice

From: Logistics of an advanced therapy medicinal product during COVID-19 pandemic in Italy: successful delivery of mesenchymal stromal cells in dry ice

Delivery date

Temperature (external)

Delivery time

Temperature (start)

Temperature (arrival)

Dry ice weight loss

07.04.2020

15 °C

2 h 25 min

− 86.1 °C

− 79.1 °C

2%

14.04.2020

20 °C

1 h 35 min

− 80.3 °C

− 78.9 °C

1%

05.05.2020

35 °C

24 h

− 80.6 °C

− 80.3 °C

30%

  1. Two concurrent and one prospective runs were performed. The temperature of the ATMP always remained below − 76 °C. The maximum delivery time was 24 h