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Table 1 Baseline characteristics, vital signs, laboratory parameters and statistic results of mimic-III patients with sepsis

From: Predicting 30-days mortality for MIMIC-III patients with sepsis-3: a machine learning approach using XGboost

  Death within 30 days Survival within 30 days p
Number (sample size) 889 3670  
Baseline variables and in-hospital factors
 Age (year, mean SD) 71.42 ± 15.93 63.61 ± 17.73 8.95E−36
Sex (%)
 Female 413 1609  
 Male 476 2061 0.1706
Ethnicity (%)
 White 617 (69.4%) 2642 (72.1%)  
 Black 66 (7.4%) 338 (9.2%)  
 Yellow 34 (3.8%) 145 (4%)  
 Others 172 (19.3%) 545 (14.9%) 0.005914
 Weight (kg), mean (SD) 76.91 ± 21.31 82.69 ± 28.61  
 Height (cm), mean (SD) 168.27 ± 11.66 169.51 ± 10.73  
 BMI (kg/m2), mean (SD) 27.82 ± 7.65 29.25 ± 8.91  
 Length of stay in hospital, days, mean (SD) 7.04 ± 6.3 10.99 ± 10.4  
 Length of stay in the ICU, days, mean (SD) 4.87 ± 4.99 4.66 ± 6.31  
Admission type
 MED 580 (65.2%) 1912 (52.1%)  
 CMED 86 (9.7%) 477 (13.0%)  
 Others 223 (25.1%) 1282 (34.9%) 1.36E−11
Vital signs
 Heartrate_min (times/min), mean (SD) 72.92 ± 19.16 73.08 ± 15.72 0.826205355
 Heartrate_mean (times/min), mean (SD) 91.12 ± 18.27 87.81 ± 16.15 0.00000579
 Sysbp_min (mmhg), mean (SD) 80.46 ± 20.01 90.69 ± 16.18 6.49E−36
 Diasbp_mean (mmhg), mean (SD) 58.65 ± 10.42 61.7 ± 10.08 6.62E−13
 Meanbp_min (mmhg), mean (SD) 48.41 ± 15.65 56.24 ± 13.89 6.74E−34
 Resprate_mean (times/min),mean (SD) 21.73 ± 4.68 19.54 ± 4.06 3.66E−30
 Tempc_min (℃), mean (SD) 35.77 ± 1.17 36.15 ± 0.86 1.78E−16
 Tempc_max (℃), mean (SD) 37.34 ± 1.17 37.65 ± 0.85 3.37E−11
 Spo2_mean (%), mean (SD) 96.03 ± 4.02 97.1 ± 1.96 3.06E−12
Laboratory parameters
 Aniongap_max (mmhg), mean (SD) 19.12 ± 6.26 16.17 ± 4.65 1.45E−31
 Aniongap_min (mmhg), mean (SD) 14.58 ± 4.66 12.45 ± 3.08 1.48E−30
 Creatinine_min (ng/dL), mean (SD) 1.65 ± 1.23 1.35 ± 1.39 3.89E−09
 Chloride_min (mmol/L), mean (SD) 101.67 ± 7.65 101.93 ± 6.69 0.39868745
 Hemoglobin_min (g/dL), mean (SD) 9.84 ± 2.21 10.08 ± 2.08 0.009534544
 Hemoglobin_max, (g/dL), mean (SD) 11.77 ± 2.26 12 ± 2.09 0.012634047
 Lactate_min (mmol/L), mean (SD) 2.36 ± 2.07 1.55 ± 0.81 4.26E−24
 Platelet_min (109/L), mean (SD) 189.73 ± 125.29 195.98 ± 108.29 0.207608419
 Potassium_min (mmol/L), mean (SD) 3.84 ± 0.7 3.71 ± 0.54 0.00000328
 Sodium_min (mmol/L), mean (SD) 136.27 ± 6.62 136.08 ± 5.35 0.454879474
 Sodium_max (mmol/L), mean (SD) 141.28 ± 6.8 140.51 ± 5.03 0.003570629
 Bun_min (mmol/L), mean (SD) 36.09 ± 25.43 24.22 ± 19.69 8.45E−31
 Bun_max (mmol/L), mean (SD) 42.88 ± 28.49 30.23 ± 24.39 1.12E−27
 Wbc_min (109/L), mean (SD) 12.54 ± 12.22 10.41 ± 6.55 4.81E−06
 Wbc_max (109/L), mean (SD) 17.54 ± 19.99 14.8 ± 9.87 0.000293182
 Inr_max, mean (SD) 2.12 ± 1.79 1.61 ± 1.34 2.89E−14
 Urine output 1225.29 ± 1307.53 1993.04 ± 1551.57 2.82E−48
Score system
 SOFA 8.02 ± 4.33 5.22 ± 2.85 2.74E−55
 qSOFA 2.15 ± 0.64 1.9 ± 0.69 4.60E−21
 SAPS II 54.67 ± 16.37 37.51 ± 13.22 2.2E−16
Advanced life support
 Mechanical ventilation 531 (59.69%) 1668 (45.55%)  
 Renal replacement therapy 53 (5.95%) 135 (3.61%) 0.2503
Accompanied diseases (comorbidity)
 Diabetes 246 (27.64%) 2631 (71.70%)  
 Malignant tumour 116 (13.05%) 160 (4.37%)  
 Others 527 (59.31%) 879 (23.93%) 2.20E−16
Common sources of infection
 Blood culture 418 (47%) 1343 (36.6%)  
 MRSA screen 267 (30%) 1384 (37.72%)  
 Urine 151 (17%) 642 (17.5%)  
 Swab 18 (2%) 70 (1.9%)  
 Others 35 (4%) 231 (6.3%) 7.82E−08
Outcome
 Within 30-days mortality 19.50% 80.50%  
  1. MED medical-general service for internal medicine, CMED cardiac medical-for non-surgical cardiac related admissions, sysbp systolic blood pressure, diasbp diastolic blood pressure, meanbp mean blood pressure, resprate respiratary rate, tempc temperature, bun blood urea nitrogen, wbc white blood cell, INR international normalized ratio, sofa sequential organ failure assessment, qSOFA quick SOFA, SAPS II simplified acute physiology score II, Spo2 oxyhemoglobin saturation, Max maximum, Min minimum