Table 2 Reported cell subsets in the included studies including the effect of Aza/DAC on the reported cell subset
From: Immune responses to azacytidine in animal models of inflammatory disorders: a systematic review
Author first, last, year, journal | Disease | FOXP3/Treg | CD45/Leukocytes | Granulocytes | Lymphocytes | Macrophages | CD3/Tcell | CD4/Thelper | CD8/Tcyt | B220/B-cells |
|---|---|---|---|---|---|---|---|---|---|---|
Sánchez-Aberca, Pérez-Simon, 2010, The American Society of Hematology | GvHD | Equal or ↑ |  |  |  |  |  |  |  |  |
Choi, Dipersio, 2010, The American Society of Hematology | GvHD | ↑ |  |  |  |  | ↑ |  |  | ↑ |
Fransolet, Baron, 2016, Journal of Hematology and Oncology | GvHD | ↑ | ↓ |  | ↓ |  |  | Equal or ↓ |  |  |
Cooper, DiPersio, 2017, Journal of Immunology | GvHD | ↑ |  |  |  |  | ↑ |  |  | ↑ |
Ehx,Baron 2017 OncoImmunology | GvHD | ↑ |  |  |  |  |  |  |  |  |
Guo, Jiang, 2013, Transplant Immunology | Organ rejection | ↑ |  |  |  |  |  |  | ↓ |  |
Hong J, Yang, 2013, Transplant Immunology | Organ rejection | ↑ |  |  |  |  |  |  |  |  |
Zheng, Zhao, 2009, J Mol Med | Diabetes | ↑ |  |  |  |  |  | ↑ | ↑ |  |
Chen, Dong, 2019, Kidney International | Diabetes | ↑ |  |  |  |  |  | ↓ |  |  |
Cao, Xua, 2014, Endocrinology | Atherosclerosis |  |  |  |  |  |  | Equal | ↓ | ↓ |
Li, Tang, 2016, The American Physiological Society | Biliary Arthresia | ↑ |  |  |  |  |  |  |  |  |
Yoshida, Izni, 1990, European Journal of Immunology | SLE | Â | Â | Â | Â | Â | Â | Equal | Equal | Equal |
Li, Tsokos, 2018, JCI Insight | SLE | ↑ |  |  |  |  |  |  |  |  |
Singer, D'alessio, 2014, Am Journal of Respiratory Cell and Molecular Biology | ARDS | ↑ |  | ↓ |  |  |  |  |  |  |
Thangavel, Rajasingh, 2014, Am Journal of Pathology | ARDS | Â | Â | Equal | Â | Â | Â | Â | Â | Â |
Thangavel, Rajasingh, 2015, Journal of Cell Science | ARDS | Â | Equal | Â | Â | Equal | Â | Â | Â | Â |
Wu, Kuo, 2012, Allergy and Immunology | Asthma | ↑ |  | ↓ | ↓ | ↓ |  |  |  |  |
Brand, Renz, 2011, Journal of Allergy and Clinical Immunology | Asthma |  | ↓ | ↓ | ↓ | ↓ |  |  |  |  |
Tóth, Rauch, 2019, Arthritis & Rheumatology | RA |  |  |  |  |  |  |  |  | ↓ |
Chan, Wu, 2014, Molecular Medicine | MS | ↑ |  |  | ↓ |  |  |  |  |  |
Wang X, Tao, 2017, Oncotarget | MS | Equal or ↓ | ↓ |  |  |  |  | ↓ | ↓ |  |
Mangano, Nicoletti, 2014, Journal of Cellular Physiology | MS | ↑ | ↓ |  |  |  |  | ↓ |  |  |
Fagone, Nicoletti, 2018, Journal of Neuroimmunology | GBS | ↑ | Equal |  |  |  | Equal | Equal | Equal |  |