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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Dysregulated PDGFR alpha expression and novel somatic mutations in colorectal cancer: association to RAS wild type status and tumor size

Fig. 3

The effect of synonymous variations on mRNA secondary structure. Sanger sequencing chromatograms show the wild and mutated sequence of synonymous PDGFRA exon 18 variations (c.2472C > T, c.2481A > T, c.2496G > A, c.2514C > T, c.2517G > T and c.2520C > A). The effect of synonymous variations on partial mRNA (123pb) secondary structure is compared to the reference sequence at the same position (arrows)

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