Fig. 3From: Dysregulated PDGFR alpha expression and novel somatic mutations in colorectal cancer: association to RAS wild type status and tumor sizeThe effect of synonymous variations on mRNA secondary structure. Sanger sequencing chromatograms show the wild and mutated sequence of synonymous PDGFRA exon 18 variations (c.2472C > T, c.2481A > T, c.2496G > A, c.2514C > T, c.2517G > T and c.2520C > A). The effect of synonymous variations on partial mRNA (123pb) secondary structure is compared to the reference sequence at the same position (arrows)Back to article page