Fig. 6From: Putative positive role of inflammatory genes in fat deposition supported by altered gene expression in purified human adipocytes and preadipocytes from lean and obese adipose tissuesComparison of inflammatory gene expression in lean and obese adipogenesis. a A scatter plot was constructed with a total of 7,118 genes commonly altered in lean and obese adipogenesis (i.e., common DEGs between ‘Lean_Ag-DEGs’ and ‘Obese_Ag-DEGs’). Log2FC values of gene expression in ‘Lean_Ag-DEGs’ were plotted against log2FC values of gene expression in ‘Obese_Ag-DEGs’. The gray and red dots represent the total 7118 common DEGs and the inflammatory genes, respectively. The blue dashed diagonal line indicates a regression line for the values, while the black diagonal line indicates the line of equality (y = x). The correlation coefficient (γ) was calculated by Pearson correlation test. b Boxplots of gene expression values for three selected genes, i.e., IL-6, TNF-α, and IL-1β were constructed; the box plots in the left panel provide a comparison of the expression of these three genes in lean and obese AC samples, while the box plots in the right panel provide a comparison between ‘[AC/preAC]_lean’ (i.e., expression levels of these three genes in AC and preAC samples derived from the lean adipogenesis condition) and ‘[AC/preAC]_obese’ (i.e., expression levels of these three genes in AC and preAC samples derived from the obese adipogenesis condition). The statistical test was performed by the ‘Wilcoxon rank-sum test’. ‘*’, ‘**’, and ‘***’ indicate P < 0.05, P < 0.01, and P < 0.001, respectively, while ‘ns’ indicates P > 0.05Back to article page