Factors influencing cancer genetic somatic mutation test ordering by cancer physician

Table 4 Backward stepwise logistic regression model for survey results identifying the predictors of somatic mutation test ordering

Predictor variable	No. of somatic mutation tests ordered
	Sig.	OR	95% CI for OR
	Sig.	OR	Lower	Upper
Step 1
Years of experience	0.797	1.07	0.62	1.86
Specialty	0.013	3.52	1.30	9.53
Unique number of patients	0.733	0.95	0.68	1.31
TMP vs TP^a	0.819	0.98	0.80	1.19
Confidence in interpreting	0.072	3.14	0.91	10.87
Confidence in making treatment recommendations	0.126	2.48	0.77	7.96
Step 2
Years of experience	0.793	1.08	0.62	1.86
Specialty	0.013	3.55	1.31	9.60
Unique number of patients	0.744	0.95	0.69	1.31
Confidence in interpreting	0.062	3.21	0.94	10.93
Confidence in making treatment recommendations	0.124	2.49	0.78	7.97
Step 3
Specialty	0.013	3.53	1.31	9.52
Unique number of patients	0.726	0.94	0.69	1.30
Confidence in interpreting	0.055	3.28	0.97	11.08
Confidence in making treatment recommendations	0.130	2.42	0.77	7.63
Step 4
Specialty	0.012	3.57	1.33	9.61
Confidence in interpreting	0.045	3.41	1.03	11.32
Confidence in making treatment recommendations	0.132	2.41	0.77	7.60
Step 5
Specialty	0.011	3.56	1.34	9.46
Confidence in interpreting	0.000	5.93	2.23	15.75

Bold denoted p < 0.05
^a Measured on a 10 cm line, with tumour pathology on the left and tumour molecular profile on the right

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