Fig. 3

Genomic profile characteristics of the Korean metastatic breast PDX model. a Somatic mutations in our PDX model are arranged according to frequency. The samples are arranged by their subtype. The mutation burden of each sample is also presented. The genes are listed according to their mutation frequency, from high to low. b The mutation frequencies of TP53, PIK3CA, and ESR1 were analyzed by subtype and are represented by a bar graph (a comparison with the other datasets is also shown). c Mutation burden of each subtype. d The mutation frequency of actionable mutation genes. The mutations that were detected in the patient and PDX tumor samples derived from the same patient were compared