Fig. 2

The statistics of PDX model establishment and fidelity between the PDX model and donor. a The total numbers of enrollment and take cases and those subdivided (enrollment cases and take cases) are represented by a bar graph. The take rate is also marked. b The take rate by tissue origin is represented by a bar graph. c The take rate by Ki-67 expression in patient tissues is represented by a bar graph. d The subtype composition of the established PDX model and its tissue of origin. The subtype was compared with PDX IHC analysis and clinical records. e The somatic mutation patterns of the patient tissue and its corresponding PDX model. The case number with IMT indicates the results of patient tissue analysis, and the case number with IMX indicates the results of PDX tissue analysis. The list of genes is ordered by mutational frequency, and the number of somatic mutations of each sample is marked in the figure. f CNV concordance between patient and PDX tissues. The correlation was determined by Pearson’s correlation analysis using the log2-fold change value of each sample