Characteristics | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Age | ||||
60–69 | Reference | Reference | ||
70–79 | 1.074 (1.028–1.122) | 0.001 | 1.075 (1.029–1.124) | 0.001 |
≥ 80 | 1.511 (1.437–1.588) | < 0.001 | 1.185 (1.124–1.249) | < 0.001 |
Sex | ||||
Male | Reference | Reference | ||
Female | 0.871 (0.838–0.905) | < 0.001 | 0.862 (0.828–0.898) | < 0.001 |
Race | ||||
White | Reference | Reference | ||
Black | 1.115 (1.049–1.184) | < 0.001 | 0.884 (0.831–0.940) | < 0.001 |
Asian or Pacific Islander | 1.152 (1.048–1.265) | 0.003 | 0.880 (0.800–0.968) | 0.008 |
American Indian/Alaska Native | 1.110 (0.876–1.407) | 0.388 | 1.039 (0.819–1.317) | 0.754 |
Marital | ||||
Married | Reference | Reference | ||
Unmarried | 1.146 (1.103–1.190) | < 0.001 | 1.042 (1.000–1.085) | 0.049 |
Unknown | 0.996 (0.901–1.102) | 0.944 | 0.945 (0.853–1.046) | 0.273 |
Site | ||||
Main bronchus | Reference | Reference | ||
Upper lobe, lung | 0.476 (0.438–0.517) | < 0.001 | 0.717 (0.660–0.779) | < 0.001 |
Middle lobe, lung | 0.480 (0.424–0.544) | < 0.001 | 0.768 (0.677–0.871) | < 0.001 |
Lower lobe, lung | 0.484 (0.445–0.528) | < 0.001 | 0.737 (0.676–0.804) | < 0.001 |
Overlapping lesion of lung | 0.552 (0.453–0.672) | < 0.001 | 0.866 (0.710–1.055) | 0.152 |
Lung, NOS | 1.019 (0.914–1.135) | 0.735 | 0.797 (0.712–0.892) | < 0.001 |
Laterality | ||||
One side | Reference | Reference | ||
Bilateral | 2.393 (2.006–2.855) | < 0.001 | 0.890 (0.738–1.074) | 0.224 |
Grade | ||||
I | Reference | Reference | ||
II | 0.895 (0.801–0.999) | 0.048 | 0.962 (0.861–1.074) | 0.492 |
III | 1.104 (0.990–1.232) | 0.075 | 1.013 (0.908–1.130) | 0.814 |
IV | 1.288 (1.036–1.600) | 0.023 | 1.112 (0.894–1.382) | 0.340 |
AJCC stage | ||||
I | Reference | Reference | ||
II | 2.257 (2.099–2.426) | < 0.001 | 2.544 (2.363–2.738) | < 0.001 |
III | 4.080 (3.839–4.336) | < 0.001 | 3.689 (3.447–3.948) | < 0.001 |
IV | 8.800 (8.294–9.337) | < 0.001 | 6.245 (5.830–6.691) | < 0.001 |
Surgery | ||||
Yes | Reference | Reference | ||
No | 5.003 (4.759–5.259) | < 0.001 | 3.643 (3.421–3.879) | < 0.001 |
Radiation | ||||
Yes | Reference | Reference | ||
No | 0.798 (0.768–0.828) | < 0.001 | 1.483 (1.421–1.548) | < 0.001 |
Chemotherapy | ||||
Yes | Reference | Reference | ||
No | 0.871 (0.839–0.905) | < 0.001 | 1.812 (1.736–1.892) | < 0.001 |
Insurance | ||||
Yes | Reference | Reference | ||
No | 1.228 (1.162–1.297) | < 0.001 | 1.033 (0.977–1.094) | 0.255 |