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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Conformational changes in myeloperoxidase induced by ubiquitin and NETs containing free ISG15 from systemic lupus erythematosus patients promote a pro-inflammatory cytokine response in CD4+ T cells

Fig. 2

NETs from SLE patients are enriched in ISG15. a Western Blot analysis of LPS induced NETs from SLE patients and healthy controls (n = 2 subjects per group) was performed and quantification was done by densitometry. MPO was used as a loading control. Representative blots for ISG15 expression are included (a) and increased expression of ISG15 in NETs from SLE patients (n = 5) vs healthy controls (n = 3) is shown in b. *p < 0.05

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