Table 1 KEGG pathway enrichment analysis of DLDTI results
Class | KEGG term | Count | P value |
|---|---|---|---|
Signal transduction | PI3K-Akt signaling pathway | 36 | 2.49E−17 |
|  | Neuroactive ligand-receptor interaction | 32 | 6.04E−17 |
|  | MAPK signaling pathway | 29 | 1.08E−13 |
|  | Calcium signaling pathway | 26 | 1.01E−15 |
|  | Rap1 signaling pathway | 22 | 2.99E−11 |
|  | cGMP-PKG signaling pathway | 20 | 2.99E−11 |
|  | cAMP signaling pathway | 16 | 3.83E−07 |
Metabolism | Metabolism of xenobiotics by cytochrome P450 | 23 | 4.27E−20 |
|  | Steroid hormone biosynthesis | 17 | 1.28E−14 |
|  | Retinol metabolism | 15 | 5.89E−12 |
Immune system | Complement and coagulation cascades | 21 | 3.06E−17 |
|  | Th17 cell differentiation | 15 | 1.77E−09 |
Others | Regulation of actin cytoskeleton | 16 | 6.90E-07 |
| Â | Gap junction | 15 | 2.74E-10 |
| Â | Fluid shear stress and atherosclerosis | 15 | 2.91E-08 |