Table 3 Immune mediators in BAL fluid of participants
Analyte (pg/mL) | Day 0 (n = 12) | Day 3 (n = 8) | Slow resolver Day 0 (n = 5) | Fast resolver Day 0 (n = 7) | Slow resolver Day 3 (n = 4) | Fast resolver Day 3 (n = 4) |
|---|---|---|---|---|---|---|
TNFSF13 | 4366.9 ± 3376.7 | 2245.9 ± 1666.1 | 4188.7 ± 4860.0 | 4494.2 ± 2260.9 | 1463.44 ± 1654.4 | 3028.4 ± 1451.5 |
TNFSF13B | 4556.0 ± 3347.2 | 1877.4 ± 1598.0 | 5204.0 ± 4960.8 | 4093.1 ± 1879.8 | 977.4 ± 664.0 | 2777.3 ± 1832.5 |
TNFRSF8 | 339.8 ± 218.5 | 201.5 ± 124.0 | 400.4 ± 324.9 | 296.5 ± 109.0 | 112.7 ± 23.6 | 290.3 ± 119.4 |
sCD163 | 9146.0 ± 3313.6 | 6855.8 ± 3156.6 | 8286.0 ± 3835.9 | 9760.4 ± 3043.7 | 4556.7 ± 1066.2 | 9154.9 ± 2831.4 |
Chitinase-3-like 1 | 14,719.3 ± 2663.3 | 13,691.3 ± 2672.3 | 15,390.7 ± 3510.7 | 14,239.8 ± 2035.5 | 13,036.8 ± 1800.7 | 14,345.9 ± 3503.9 |
gp130/IL-6RB | 6604.1 ± 2809.5 | 4831.8 ± 2998.2 | 5784.4 ± 3518.3 | 7189.7 ± 2293.1 | 4154.8 ± 3480.2 | 5508.9 ± 2764.1 |
IFN-α2 | 66.0 ± 23.5 | 46.6 ± 13.2 | 74.1 ± 27.1 | 60.1 ± 20.7 | 40.1 ± 7.9 | 53.1 ± 15.2 |
IFN-β | 126.7 ± 37.9 | 93.8 ± 32.1 | 126.7 ± 54.3 | 126.7 ± 26.0 | 77.0 ± 7.6 | 110.6 ± 39.9 |
IFN-γ | 66.5 ± 28.5 | 50.5 ± 23.1 | 65.2 ± 28.7 | 67.5 ± 30.6 | 38.6 ± 11.0 | 62.4 ± 27.4 |
IL-2 | 95.3 ± 38.9 | 70.6 ± 21.7 | 90.3 ± 36.6 | 98.9 ± 42.9 | 58.3 ± 20.1 | 82.9 ± 16.9 |
sIL-6Rα | 1495.8 ± 1426.1 | 872.6 ± 660.4 | 1998.1 ± 2196.6 | 1136.9 ± 389.3 | 526.8 ± 341.2 | 1218.4 ± 763.2 |
IL-8 | 7447.5 ± 5125.6 | 8164.9 ± 9002.5 | 7629.7 ± 4262.7 | 7317.3 ± 6000.4 | 13,239.5 ± 10,755.2 | 3090.2 ± 2181.9 |
IL-10 | 655.3 ± 1948.8 | 107.5 ± 72.6 | 1435.1 ± 3023.2 | 98.3 ± 28.2 | 81.8 ± 23.6 | 133.3 ± 99.9 |
IL-11 | 501.7 ± 517.4 | 258.1 ± 272.3 | 221.4 ± 211.5 | 701.9 ± 590.6 | 99.9 ± 119.9 | 416.3 ± 303.2 |
IL-12 (p40) | 104.6 ± 29.6 | 78.5 ± 27.0 | 109.1 ± 37.9 | 101.4 ± 24.9 | 57.5 ± 15.1 | 99.4 ± 17.5 |
IL-12 (p70) | 31.8 ± 6.4 | 28.9 ± 3.4 | 31.6 ± 7.2 | 31.9 ± 6.4 | 29.8 ± 3.6 | 28.1 ± 3.5 |
IL-19 | 76.2 ± 45.3 | 124.0 ± 189.9 | 92.0 ± 68.8 | 64.9 ± 15.6 | 188.6 ± 270.1 | 59.4 ± 6.3 |
IL-20 | 75.5 ± 26.8 | 53.3 ± 12.9 | 74.3 ± 26.3 | 76.4 ± 29.3 | 51.0 ± 17.0 | 55.6 ± 9.2 |
IL-22 | 78.1 ± 35.6 | 60.9 ± 14.4 | 89.6 ± 54.7 | 69.9 ± 12.0 | 64.4 ± 17.9 | 57.4 ± 11.4 |
IL-26 | 106.3 ± 32.6 | 79.9 ± 28.0 | 110.2 ± 42.8 | 103.5 ± 26.5 | 56.0 ± 15.1 | 103.8 ± 8.9 |
IL-27 | 54.3 ± 27.1 | 35.8 ± 7.2 | 54.5 ± 20.3 | 54.1 ± 32.8 | 34.4 ± 10.5 | 37.3 ± 1.9 |
IL-28A/IFN-λ2 | 82.2 ± 33.8 | 49.3 ± 20.2 | 82.3 ± 27.3 | 82.1 ± 40.0 | 36.8 ± 9.6 | 61.8 ± 21.0 |
IL-29/IFN-λ1 | 39.4 ± 13.7 | 30.2 ± 7.7 | 39.5 ± 12.8 | 39.4 ± 15.4 | 26.5 ± 4.6 | 33.8 ± 9.0 |
IL-32 | 111.3 ± 21.0 | 104.2 ± 31.2 | 116.5 ± 21.7 | 107.6 ± 21.3 | 114.5 ± 32.7 | 93.9 ± 30.3 |
IL-34 | 78.4 ± 10.9 | 67.0 ± 17.7 | 75.5 ± 7.9 | 80.5 ± 12.7 | 71.3 ± 19.6 | 62.8 ± 17.2 |
IL-35 | 140.8 ± 39.9 | 113.6 ± 20.8 | 139.4 ± 37.1 | 141.9 ± 44.8 | 106.5 ± 16.5 | 120.8 ± 24.5 |
LIGHT/TNFSF14 | 67.8 ± 12.9 | 66.8 ± 33.2 | 70.2 ± 15.1 | 66.0 ± 12.0 | 81.9 ± 42.8 | 51.8 ± 12.0 |
MMP-1 | 161.3 ± 103.2 | 101.0 ± 31.1 | 186.8 ± 158.8 | 143.1 ± 42.2 | 87.4 ± 33.2 | 114.6 ± 25.9 |
MMP-2 | 143.6 ± 76.9 | 125.7 ± 122.3 | 153.7 ± 109.2 | 136.3 ± 52.6 | 183.0 ± 158.6 | 68.4 ± 31.3 |
MMP-3 | 69.5 ± 33.0 | 52.3 ± 19.2 | 69.6 ± 28.5 | 69.5 ± 38.1 | 51.6 ± 24.4 | 52.9 ± 16.2 |
Osteocalcin | 108.4 ± 43.2 | 69.6 ± 16.6 | 94.3 ± 21.2 | 118.6 ± 53.2 | 61.6 ± 7.2 | 77.7 ± 20.4 |
Osteopontin | 14,510.9 ± 7668.3 | 10,381.1 ± 7674.8 | 13,149.5 ± 9792.5 | 15,483.4 ± 6420.9 | 4122.9 ± 5110.7 | 16,639.3 ± 2623.1 |
Pentraxin | 4073.1 ± 4227.4 | 1865.2 ± 1638.8 | 3469.5 ± 2253.2 | 4504.3 ± 5372.0 | 866.1 ± 816.3 | 2864.3 ± 1714.2 |
sTNF-R1 | 5390.5 ± 1949.5 | 4198.8 ± 1573.7 | 5368.0 ± 2904.4 | 5406.6 ± 1158.9 | 3808.4 ± 2203.5 | 4589.3 ± 718.9 |
sTNF-R2 | 2085.6 ± 2343.4 | 934.7 ± 483.8 | 2687.1 ± 3666.2 | 1656.0 ± 768.2 | 775.2 ± 513.4 | 1094.3 ± 463.5 |
TSLP | 261.1 ± 457.7 | 80.8 ± 66.7 | 134.0 ± 110.0 | 351.9 ± 594.1 | 39.5 ± 9.0 | 122.1 ± 75.8 |
TWEAK/TNFSF12 | 183.1 ± 65.1 | 184.2 ± 88.6 | 184.7 ± 62.1 | 182.1 ± 72.1 | 232.8 ± 78.6 | 135.6 ± 76.5 |