From: Detection of novel coronavirus (SARS-CoV-2) RNA in peripheral blood specimens
Study | Sample types | Detection rate % | RNA extraction method | RNA detection method | Confirmed test | Stage of disease | Refs. |
---|---|---|---|---|---|---|---|
Zheng et al. | Serum | 41 | MagNA Pure 96 | RT-qPCR | Sputum and saliva samples | After admission | [12] |
Wölfel et al. | Serum | 0 | – | RT-qPCR | Oro- or naso-pharyngeal swab specimens | Between 2 and 4 days after the onset of symptoms | [17] |
Ling et al. | Serum | 0 | Magnetic bead-method nucleic acid extraction kit | RT-qPCR | Oropharyngeal swab | After admission | [18] |
Zhang et al. | Whole blood and serum | Whole blood: 40 Serum: 20 | High Pure Viral RNA Kit (Roche) | RT-qPCR | Oral swabs and anti-SARSr-CoV IgG and IgM ELISA test | After admission | [20] |
Wang et al | Blood | 1 | – | RT-qPCR | Nasopharyngeal swabs | 1 to 3 days after hospital admission | [23] |
Chen et al | Serum | 10.4 | – | RT-qPCR | Throat swabs | Immediately after admission | [15] |
Chen et al | Blood | 10.5 | Nucleic Acid Isolation Kit (Da’an Gene Corporation, Cat: DA0630) | RT-qPCR | Anal and pharyngeal swab | _ | [16] |
Huang et al | Plasma | 15 | Direct-zol RNA Miniprep kit | RT-qPCR | Laboratory-confirmed 2019-nCoV infection by real-time RT-PCR and next-generation sequencing | _ | [13] |
Peng et al | Blood | 22.2 | Nucleic Acid Extraction and Purification Kit (SUPI‐1017; Supbio, Guangzhou, China) | RT-qPCR | Oropharyngeal swabs | After admission | [10] |
Lescure et al | Serum | 0 | Extraction NucleoSpin Dx Virus kit (Macherey Nagel, Düren, Germany) | RT-qPCR | Nasopharyngeal swabs | After hospital admission | [24] |
Kujawski et al | Serum | 9.09 | – | RT-qPCR and whole genome sequencing | Nasopharyngeal swabs and f laboratory-confirmed SARS-CoV-2 | After admission | [11] |
Chan et al | Serum | 16.6 | QIAamp Viral RNA Mini Kit (Qiagen, Hilden, Germany) | RT-qPCR | CT scan and laboratory-confirmed SARS-CoV-2 | _ | [25] |