Allogeneic administration of human umbilical cord-derived mesenchymal stem/stromal cells for bronchopulmonary dysplasia: preliminary outcomes in four Vietnamese infants

Table 2 Release criteria of allo-UC-MSC administration

Transplantation	Patient 1		Patient 2		Patient 3		Patient 4
Transplantation	1st	2nd	1st	2nd	1st	2nd	1st	2nd
Cell doses (× 10⁶ cells/kg)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
Cell viability (%)	97	97	96	98	98	98	97	89
CD73 (%)	97.9	98.5	98.5	98.3	98.4	99.63	99.5	99.6
CD90 (%)	100	100	100	100	100	99.7	100	99.9
CD105 (%)	100	100	100	100	100	100	100	100
Negative markers* (%)	0.9	0.3	0.3	0.7	0.1	0.1	0.0	0.0
Microorganism and fungal tests	Negative
Mycoplasma	Negative
Endotoxin (EU/ml)	< 0.1	< 0.05	< 0.1	< 0.1	0.073	< 0.05	< 0.05	< 0.05
Karyotyping	46, XY, 16qh +
CFU assay (CFU per 1000 cells)	519 ± 80
Adipogenesis	Pass
Chondrogenesis	Pass
Osteogenesis	Pass

ISSN: 1479-5876