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Table 1 General characterization of patients enrolled in the study

From: Allogeneic administration of human umbilical cord-derived mesenchymal stem/stromal cells for bronchopulmonary dysplasia: preliminary outcomes in four Vietnamese infants

Characteristics Patient 1 Patient 2 Patient 3 Patient 4
DOB 25/05/2018 25/05/2018 01/08/2018 07/07/2018
Gestational age at birth, weeks 24 (+ 5 days) 24 (+ 5 days) 34 28
Birth weight (grams) 720 650 2400 1400
Sex Female Female Male Female
Prenatal steroids used Yes Yes No No
Pulmonary hypertension Yes Yes No Yes
Mechanical ventilation duration before transplantation 3.5 months 4.5 months 1 month 3 months
PaCO2 level (mmhg) before transplantation 37.9 68 59 38.6
HCO3– (mmHg) before transplantation 29.1 41.3 47.2 29.5
Oxygen support before transplantation Nasal cannula 0.5 l/min Nasal cannula 1.0 l/min Nasal cannula 1.0 l/min Nasal cannula 0.5 l/min
PaCO2 at 6 months 38 32.8 28.6 39.8
SpO2 (%) FiO2 (21%) before transplantation 75 91 70 91
SpO2 at 6 months 100 95 99 97
SpO2 at 12 months 100 100 100 97
Postnatal age at UC-MSC administration, days 144 151 173 160
Weight at UC-MSC administration (grams) 3600 4000 5400 3800
Duration from birth to discharge (days) 161 161 183 173
Duration from transplantation to independence from oxygen support 3 days after the 2nd transplantation 2 months 2 months 4 days after the first transplantation
Chest X-ray before transplantation Diffuse fibrosis, atelectasis, diffuse haziness Diffuse fibrosis, atelectasis, diffuse haziness Air trapping, diffuse fibrosis, atelectasis, diffuse haziness Air trapping, diffuse fibrosis, atelectasis, diffuse haziness
Chest X-ray 12 months after transplantation Reduction in fibrosis Reduction in fibrosis Normal Normal