DOB
|
25/05/2018
|
25/05/2018
|
01/08/2018
|
07/07/2018
|
Gestational age at birth, weeks
|
24 (+ 5 days)
|
24 (+ 5 days)
|
34
|
28
|
Birth weight (grams)
|
720
|
650
|
2400
|
1400
|
Sex
|
Female
|
Female
|
Male
|
Female
|
Prenatal steroids used
|
Yes
|
Yes
|
No
|
No
|
Pulmonary hypertension
|
Yes
|
Yes
|
No
|
Yes
|
Mechanical ventilation duration before transplantation
|
3.5 months
|
4.5 months
|
1 month
|
3 months
|
PaCO2 level (mmhg) before transplantation
|
37.9
|
68
|
59
|
38.6
|
HCO3– (mmHg) before transplantation
|
29.1
|
41.3
|
47.2
|
29.5
|
Oxygen support before transplantation
|
Nasal cannula 0.5 l/min
|
Nasal cannula 1.0 l/min
|
Nasal cannula 1.0 l/min
|
Nasal cannula 0.5 l/min
|
PaCO2 at 6 months
|
38
|
32.8
|
28.6
|
39.8
|
SpO2 (%) FiO2 (21%) before transplantation
|
75
|
91
|
70
|
91
|
SpO2 at 6 months
|
100
|
95
|
99
|
97
|
SpO2 at 12 months
|
100
|
100
|
100
|
97
|
Postnatal age at UC-MSC administration, days
|
144
|
151
|
173
|
160
|
Weight at UC-MSC administration (grams)
|
3600
|
4000
|
5400
|
3800
|
Duration from birth to discharge (days)
|
161
|
161
|
183
|
173
|
Duration from transplantation to independence from oxygen support
|
3 days after the 2nd transplantation
|
2 months
|
2 months
|
4 days after the first transplantation
|
Chest X-ray before transplantation
|
Diffuse fibrosis, atelectasis, diffuse haziness
|
Diffuse fibrosis, atelectasis, diffuse haziness
|
Air trapping, diffuse fibrosis, atelectasis, diffuse haziness
|
Air trapping, diffuse fibrosis, atelectasis, diffuse haziness
|
Chest X-ray 12 months after transplantation
|
Reduction in fibrosis
|
Reduction in fibrosis
|
Normal
|
Normal
|