Fig. 2

Effect of hypoxia on monocyte migration. The red cross represents the mean end point of the trajectory of cells subjected to an oxygen gradient (a), under normoxic conditions (b) or subjected to a gradient of heat-inactivated hypoxia-inducing enzymes (c). Each graph shows one representative experiment, containing migration data of at least N = 20 cells. T1, time point < 5 min; T2, time point = 2.5 h; T3, time point = 5 h; H, hypoxia; HE, heat inactivated enzymes (GO and CAT)