Table 1 Baseline characteristics of all the infants enrolled in study
Characteristic | Control n = 948 | rhEPO n = 950 | P |
|---|---|---|---|
Male, n (%) | 581 (61.3) | 573 (60.3) | 0.672 |
Gestational age (weeks), mean ± SD | 29.9 ± 1.5 | 29.8 ± 1.8 | 0.413 |
Birth weight (gram), mean ± SD | 1318 ± 252 | 1307 ± 211 | 0.298 |
Maternal age(years), mean ± SD | 29.6 ± 5.4 | 30.0 ± 5.4 | 0.124 |
Maternal hypertension, n (%) | 199 (21.0) | 185 (19.5) | 0.424 |
Premature rupture of membrane, n (%) | 255 (26.9) | 257 (27.1) | 0.959 |
Twins/multiple births, n (%) | 137 (14.5) | 110 (11.6) | 0.066 |
Caesarean section, n (%) | 403 (42.5) | 382 (40.2) | 0.328 |
Surfactant administration, n (%) | 410 (43.2) | 405 (42.6) | 0.817 |
Clinical chorioamnionitis, n (%) | 19 (2.0) | 18 (1.9) | 0.870 |
RDS | |||
 Grade 1, n (%) | 367 (38.7) | 356 (37.5) | 0.603 |
 Grade 2, n (%) | 79 (8.3) | 76 (8.0) | 0.802 |
 Grade ≥ 3, n (%) | 45 (4.7)) | 43 (4.5) | 0.828 |
CPAP, n (%) | 466 (49.2) | 458 (48.2) | 0.713 |
Requirement of oxygen, n (%) | 804 (84.8) | 780 (82.1) | 0.122 |
Invasive mechanical ventilation, n (%) | 327 (34.5) | 291 (30.6) | 0.078 |
Early-onset sepsis, n (%) | 167 (17.6) | 194 (20.4) | 0.128 |