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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Gene correlation network analysis to identify regulatory factors in sepsis

Fig. 6

GO enrichment analysis for the black module. a The upset plot showing overlap of genes across enriched biological pathways. Biological pathways such as myeloid leukocyte mediated immunity, leukocyte degranulation and neutrophil mediated immunity shared large number of genes. b Dot plot showing the ordered enrichment biological pathways; the most enriched pathways included myeloid leukocyte mediated immunity and neutrophil mediated immunity. c Enriched terms were organized into a network with edges connecting overlapping gene sets. In this way, mutually overlapping gene sets are tend to cluster together, making it easy to identify functional modules; and d The category netplot depicts the linkages of genes and GO terms as a network, which is helpful to see which genes are involved in enriched pathways and genes that may belong to multiple annotation categories. The most important biological pathways in the module involves the immune response, including the immune response including myeloid leukocyte mediated immunity, neutrophil mediated immunity, leukocyte degranulation and myeloid cell activation

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