Fig. 2

Gene differential expression analysis (sepsis against healthy control) across modules. a Boxplot of the distribution of significance T values. The black and darkorange modules showed the most significant difference between sepsis versus controls. The red dashed lines indicate statistical significance level of two-tailed T test that have been adjusted by Bonferroni method; b fold changes of the differential expression across modules. The darkorange and black modules were among the most up-regulated modules; and c volcano plot showing differentially expressed genes between sepsis and healthy controls. Genes such as ARG1, CD177 and MMP8 were most differentially expressed