| |
ME/CFS
|
Controls
|
Mann–Whitney U test
|
|---|
|
Age (years)
|
50.6 ± 13.7
|
50.2 ± 17.5
|
p = 0.42
|
|
Gender
|
|
Female
|
28
|
28
|
NA
|
|
Male
|
7
|
7
|
NA
|
|
BMI (kg/m2)
|
24.3 ± 5.3
|
24.3 ± 4.6
|
p = 0.18
|
|
Onset of disease
|
|
Gradual
|
40%
|
NA
|
NA
|
|
Sudden
|
60%
|
NA
|
NA
|
|
Bell score
|
35.4 ± 14.1
|
96.3 ± 9.5
|
p < 0.001
|
|
SF-36
|
|
Physical function
|
44.1 ± 17.2
|
95.9 ± 7.3
|
p < 0.001
|
|
Role physical
|
5.0 ± 11.8
|
91.4 ± 26.1
|
p < 0.001
|
|
Pain
|
40.8 ± 21.6
|
87.3 ± 14.1
|
p < 0.001
|
|
General health
|
25.9 ± 14.5
|
87.3 ± 15.9
|
p < 0.001
|
|
Vitality
|
17.9 ± 15.8
|
75.4 ± 17.8
|
p < 0.001
|
|
PCSa
|
26.8 ± 7.5
|
55.1 ± 5.2
|
p < 0.001
|
|
Social function
|
33.6 ± 22.6
|
94.8 ± 12.3
|
p < 0.001
|
|
Role emotional
|
45.7 ± 45.1
|
91.9 ± 24.6
|
p < 0.001
|
|
Mental health
|
59.3 ± 19.8
|
79.7 ± 18.6
|
p < 0.001
|
|
MCSa
|
38.9 ± 10.9
|
53.4 ± 9.6
|
p < 0.001
|
|
SSSa
|
|
Fatigue
|
6.9 ± 2.5
|
1.4 ± 1.7
|
p < 0.001
|
|
Impaired memory
|
6.4 ± 2.8
|
0.8 ± 1.4
|
p < 0.001
|
|
Recurrent sore throat
|
3.9 ± 3.3
|
0.4 ± 1.1
|
p < 0.001
|
|
Tender lymph nodes
|
3.9 ± 3.1
|
0.1 ± 0.4
|
p < 0.001
|
|
Muscle tenderness or pain
|
5.5 ± 2.9
|
1.5 ± 1.9
|
p < 0.001
|
|
Joint pain
|
5.1 ± 2.9
|
1.5 ± 2.0
|
p < 0.001
|
|
Headache
|
5.0 ± 3.4
|
0.7 ± 1.4
|
p < 0.001
|
|
Disturbed sleep or waking unrefreshed
|
7.6 ± 3.0
|
1.6 ± 2.1
|
p < 0.001
|
|
Post-exertional malaise
|
7.8 ± 2.7
|
0.8 ± 1.7
|
p < 0.001
|
- aPCS Physical component score, MCS Mental component score, SSS Specific symptom severity (0 = none, 10 = very severe)
