| ME/CFS | Controls | Mann–Whitney U test |
---|---|---|---|
Age (years) | 50.6 ± 13.7 | 50.2 ± 17.5 | p = 0.42 |
Gender | |||
 Female | 28 | 28 | NA |
 Male | 7 | 7 | NA |
BMI (kg/m2) | 24.3 ± 5.3 | 24.3 ± 4.6 | p = 0.18 |
Onset of disease | |||
 Gradual | 40% | NA | NA |
 Sudden | 60% | NA | NA |
 Bell score | 35.4 ± 14.1 | 96.3 ± 9.5 | p < 0.001 |
SF-36 | |||
 Physical function | 44.1 ± 17.2 | 95.9 ± 7.3 | p < 0.001 |
 Role physical | 5.0 ± 11.8 | 91.4 ± 26.1 | p < 0.001 |
 Pain | 40.8 ± 21.6 | 87.3 ± 14.1 | p < 0.001 |
 General health | 25.9 ± 14.5 | 87.3 ± 15.9 | p < 0.001 |
 Vitality | 17.9 ± 15.8 | 75.4 ± 17.8 | p < 0.001 |
PCSa | 26.8 ± 7.5 | 55.1 ± 5.2 | p < 0.001 |
 Social function | 33.6 ± 22.6 | 94.8 ± 12.3 | p < 0.001 |
 Role emotional | 45.7 ± 45.1 | 91.9 ± 24.6 | p < 0.001 |
 Mental health | 59.3 ± 19.8 | 79.7 ± 18.6 | p < 0.001 |
MCSa | 38.9 ± 10.9 | 53.4 ± 9.6 | p < 0.001 |
SSSa | |||
 Fatigue | 6.9 ± 2.5 | 1.4 ± 1.7 | p < 0.001 |
 Impaired memory | 6.4 ± 2.8 | 0.8 ± 1.4 | p < 0.001 |
 Recurrent sore throat | 3.9 ± 3.3 | 0.4 ± 1.1 | p < 0.001 |
 Tender lymph nodes | 3.9 ± 3.1 | 0.1 ± 0.4 | p < 0.001 |
 Muscle tenderness or pain | 5.5 ± 2.9 | 1.5 ± 1.9 | p < 0.001 |
 Joint pain | 5.1 ± 2.9 | 1.5 ± 2.0 | p < 0.001 |
 Headache | 5.0 ± 3.4 | 0.7 ± 1.4 | p < 0.001 |
 Disturbed sleep or waking unrefreshed | 7.6 ± 3.0 | 1.6 ± 2.1 | p < 0.001 |
 Post-exertional malaise | 7.8 ± 2.7 | 0.8 ± 1.7 | p < 0.001 |