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Table 2 Baseline cardiovascular autonomic study with and without cardiovascular autonomic neuropathy

From: Leptin mediate central obesity on the severity of cardiovascular autonomic neuropathy in well-controlled type 2 diabetes and prediabetes

 

No CAN (n = 59)

CAN (n = 48)

P-valuea

CASS

0.5 ± 0.4

3.2 ± 1.1

 < 0.0001***

HR_DB (beats/min)

11.1 ± 7.0

5.5 ± 3.9

 < 0.0001***

Valsalva ratio

1.4 ± 0.2

1.2 ± 0.1

 < 0.0001***

Delta SBP

-3.0 (-10.0, 2.0)

-8 (-17.0, -2.0)

0.004**

E:I ratio

1.2 ± 0.1

1.1 ± 0.04

 < 0.0001***

30/15 ratio

1.1 ± 0.1

1.0 ± 0.03

 < 0.0001***

  1. Data are presented as means ± standard deviations or median (IQR); n (%).
  2. n number of cases, IQR interquartile range, CASS Composite Autonomic Scoring Scale, HR_DB heart rate response to deep breathing, CAN cardiac autonomic neuropathy, Delta SBP The change between minimum systolic blood pressure during head-up tilt and baseline systolic blood pressure
  3. aIndependent t-test, two-side, data were logarithmically transformed to improve normality
  4. *P < 0.05
  5. **P < 0.01
  6. *** = P < 0.001
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Journal of Translational Medicine

ISSN: 1479-5876

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