Fig. 1
From: High Smad7 in the early post-operative recurrence of Crohn’s disease
taken from ileal sections of 1 CD patient with no evidence of endoscopic recurrence (i0), 1 CD patient with severe endoscopic recurrence (i4), 1 CD patient with established (late) lesion and 1 normal control patient. Original magnifications 200X and 400X are shown in b and c respectively. Insets 1–3 in c show higher magnification photomicrographs; staining with control IgG is shown in the inset 4 of (c)
Smad7-positive cells accumulate in the terminal ileum of Crohn’s disease patients independently of the presence of endoscopic lesions. a Representative endoscopic pictures showing the distal ileum of 1 CD patient with no evidence of post-operative endoscopic recurrence (i0), 1 CD patient with severe endoscopic recurrence (i4), 1 CD patient with established (late) lesion and 1 normal control patient. b, c Representative photomicrographs showing Smad7-stained paraffin embedded sections of biopsy samples