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Table 3 Candidate IVs and their association with TL and IS risk under over-dominant model

From: Association between telomere length in peripheral blood leukocytes and risk of ischemic stroke in a Han Chinese population: a linear and non-linear Mendelian randomization analysis

 

Association with ln TL in controls

Association with IS in all subjects

MD (95% CI)

P

OR (95% CI)

P

rs11125529

 

0.026*

 

0.203

 C/C-A/A

0.000 (0.000, 0.000)

 

0.000 (0.000, 0.000)

 

 C/A

− 0.108 (− 0.204, − 0.013)

 

0.810 (0.580, 1.120)

 

rs412658

 

0.049*

 

0.428

 C/C-T/T

0.000 (0.000, 0.000)

 

0.000 (0.000, 0.000)

 

 C/T

− 0.089 (− 0.176, − 0.001)

 

0.890 (0.660, 1.190)

 
  1. TL telomere length, IS ischemic stroke, MD mean difference, 95% CI 95% confidence interval, OR Odds ratio
  2. * P < 0.05 is statistically significant