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Table 3 Candidate IVs and their association with TL and IS risk under over-dominant model

From: Association between telomere length in peripheral blood leukocytes and risk of ischemic stroke in a Han Chinese population: a linear and non-linear Mendelian randomization analysis

  Association with ln TL in controls Association with IS in all subjects
MD (95% CI) P OR (95% CI) P
rs11125529   0.026*   0.203
 C/C-A/A 0.000 (0.000, 0.000)   0.000 (0.000, 0.000)  
 C/A − 0.108 (− 0.204, − 0.013)   0.810 (0.580, 1.120)  
rs412658   0.049*   0.428
 C/C-T/T 0.000 (0.000, 0.000)   0.000 (0.000, 0.000)  
 C/T − 0.089 (− 0.176, − 0.001)   0.890 (0.660, 1.190)  
  1. TL telomere length, IS ischemic stroke, MD mean difference, 95% CI 95% confidence interval, OR Odds ratio
  2. P < 0.05 is statistically significant