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Table 2 Genotype distributions of SNPs in IS patients and controls

From: Association between telomere length in peripheral blood leukocytes and risk of ischemic stroke in a Han Chinese population: a linear and non-linear Mendelian randomization analysis

SNP identifier

Chr

Gene

Genotype

Controls

Cases

P

PHWE

rs11125529

2

ACYP2

   

0.433

1.000

   

C/C

202 (66.40%)

305 (70.80%)

  
   

C/A

92 (30.30%)

112 (26.00%)

  
   

A/A

10 (3.30%)

14 (3.20%)

  

rs10936599

3

MYNN

   

0.240

1.000

   

T/T

103 (33.90%)

121 (28.10%)

  
   

T/C

148 (48.70%)

225 (52.20%)

  
   

C/C

53 (17.40%)

85 (19.70%)

  

rs7726159

5

TERT

   

0.252

0.718

   

C/C

114 (37.50%)

155 (36.00%)

  
   

C/A

147 (48.40%)

195 (45.20%)

  
   

A/A

43 (14.10%)

81 (18.80%)

  

rs17653722

12

KRT80

   

0.800

0.654

   

G/G

220 (72.40%)

302 (70.10%)

  
   

G/T

76 (25.00%)

117 (27.10%)

  
   

T/T

8 (2.60%)

12 (2.80%)

  

rs8105767

19

LOC112268248

   

0.473

0.563

   

A/A

159 (52.30%)

215 (49.90%)

  
   

A/G

125 (41.10%)

177 (41.10%)

  
   

G/G

20 (6.60%)

39 (9.00%)

  

rs409627

19

ZNF676

   

0.639

0.304

   

G/G

129 (42.40%)

189 (43.90%)

  
   

G/C

145 (47.70%)

192 (44.50%)

  
   

C/C

30 (9.90%)

50 (11.60%)

  

rs412658

19

ZNF676

   

0.596

0.441

   

C/C

130 (42.80%)

188 (43.60%)

  
   

C/T

143 (47.00%)

190 (44.10%)

  
   

T/T

31 (10.20%)

53 (12.30%)

  

rs755017

20

ZBTB46

   

0.461

0.907

   

A/A

102 (33.60%)

163 (37.80%)

  
   

A/G

147 (48.40%)

199 (46.20%)

  
   

G/G

55 (18.10%)

69 (16.00%)

  
  1. IS ischemic stroke, SNP single nucleotide polymorphism, Chr chromosome
  2. P < 0.05 is statistically significant
  3. PHWE < 0.05 indicating that the SNP in control group was not satisfied Hardy–Weinberg equilibrium