Fig. 5

Kaplan–Meier analysis of the survival time for SIRT1 (a), FIS1 (b), CCNH (c), PSMC6 (d), and SUZ12 (e) in the validation dataset of 85 cases. The results show that the HD patients with high expression levels (blue line) of SIRT1, FIS1, and CCNH have a decreased overall survival time compared to those with low expression levels (red line).The remaining 2 genes showed no statistical significance between gene expression and clinical outcome of HD in the validation dataset. The dotted line represents the median survival time of those genes with different expression levels