Table 6 Binary logistic regression analyses investigating the genetic impact of T allele of rs2476601 in PTPN22 on both diseases (level 2 PD and RA) [comparison of controls without RA or level 2 PD (n = 95) vs. patients suffering from both, RA and level 2 PD (n = 26)]
From: rs2476601 in PTPN22 gene in rheumatoid arthritis and periodontitis—a possible interface?
Variables | Regression coefficient | Odds ratio | 95% confidence interval | p value | |
|---|---|---|---|---|---|
Lower | Upper | ||||
T allele of rs2476601 in PTPN22 | |||||
Age | 0.116 | 1.123 | 1.076 | 1.173 | < 0.001 |
Male gender | 0.008 | 1.008 | 0.423 | 2.402 | 0.986 |
Current smoker | 1.868 | 6.493 | 2.481 | 16.95 | < 0.001 |
P.g. positive | 2.286 | 9.804 | 3.846 | 1.04 | < 0.001 |
A.a. positive | − 2.831 | 0.059 | 0.009 | 0.368 | 0.002 |
T allele | 1.136 | 3.115 | 1.134 | 8.547 | 0.028 |