rs2476601 in PTPN22 gene in rheumatoid arthritis and periodontitis—a possible interface?

Table 5 Binary logistic regression analyses investigating the genetic impact of T allele of rs2476601 in PTPN22 on level 2 PD [comparison within the RA group: RA patients without level 2 PD (n = 85) to RA patients with level 2 PD (n = 26)]

Variables	Regression coefficient	Odds ratio	95% confidence interval		p value
Variables	Regression coefficient	Odds ratio	Lower	Upper	p value
T allele of rs2476601 in PTPN22
Age	0.020	1.020	0.992	1.049	0.162
Male gender	0.990	2.691	1.331	5.441	0.006
Current smoker	1.031	2.725	1.316	5.988	0.008
P.g. positive	1.132	3.106	1.529	6.289	0.002
A.a. positive	− 1.067	0.344	0.067	17.73	0.202
T allele	0.901	2.463	1.126	5.376	0.024

Age, gender, smoking status, and the occurrence of Porphyromonas gingivalis (P.g.) and Agregatibacter actinomycetemcomitans (A.a) were considered as confounding factors

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