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Table 4 Binary logistic regression analyses investigating the genetic impact on the prevalence of RA [comparison of the RA total group (n = 111) to the control group without RA and level 2 PD (n = 95)]

From: rs2476601 in PTPN22 gene in rheumatoid arthritis and periodontitis—a possible interface?

Variables

Regression coefficient

Odds ratio

95% confidence interval

p value

Lower

Upper

a) T allele of rs2476601 in PTPN22

Age

0.064

1.066

1.046

1.087

 < 0.001

Male gender

− 0.987

0.373

0.232

0.599

 < 0.001

Current smoker

0.712

2.041

1.276

3.257

0.003

P.g. positive

1.133

3.106

1.799

5.405

 < 0.001

A.a. positive

− 1.747

0.174

0.076

0.402

 < 0.001

T allele

0.779

2.179

1.143

4.149

0.018

b) T allele of rs2240340 in PADI4

Age

0.063

1.065

1.045

1.086

 < 0.001

Male gender

− 0.968

0.380

0.237

0.610

 < 0.001

Current smoker

0.780

2.183

1.364

3.484

0.001

P.g. positive

1.082

2.950

1.695

5.128

 < 0.001

A.a. positive

− 1.697

0.183

0.079

0.422

 < 0.001

T allele

0.425

1.529

0.965

2.42

0.070

T allele

0.493

1.637

1.013

2.645

0.044

  1. Age, gender, smoking status, and the occurrence of Porphyromonas gingivalis (P.g.) and Agregatibacter actinomycetemcomitans (A.a) were considered as confounding factors