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Table 2 Immune monitoring panel of pneumonia and stable kidney transplant recipients

From: The study of the association between immune monitoring and pneumonia in kidney transplant recipients through machine learning models

Parameters

All (n = 146)

Pneumonia (n = 46)

Stable (n = 100)

P value

Monocyte HLA-DR, MFI ± SD

1247.17 ± 764.82

931.17 ± 671.15

1392.53 ± 764.37

 < 0.001

Neutrophil CD64, MFI ± SD

254.89 ± 409.29

589.20 ± 605.44

101.11 ± 54.08

 < 0.001

CD3+ T cells/TBNK, mean ± SD (%)

74.44 ± 10.83

76.79 ± 11.71

73.35 ± 10.28

0.015

CD3+ T cells, n ± SD (cells/μl)

1024.10 ± 596.64

628.51 ± 365.86

1206.07 ± 595.30

 < 0.001

CD8+ T cells/TBNK, mean ± SD (%)

36.56 ± 10.70

36.34 ± 9.97

36.66 ± 11.06

0.903

CD8+ T cells, n ± SD (cells/μl)

506.37 ± 343.93

294.23 ± 173.57

603.95 ± 359.21

 < 0.001

CD4+ T cells/TBNK, mean ± SD (%)

37.03 ± 10.46

39.65 ± 12.98

35.82 ± 8.90

0.127

CD4+ T cells, n ± SD (cells/μl)

506.35 ± 295.64

335.48 ± 221.42

584.96 ± 293.13

 < 0.001

NK cells/TBNK, mean ± SD (%)

15.74 ± 9.60

12.78 ± 8.81

17.11 ± 9.68

0.003

NK cells, n ± SD (cells/μl)

218.43 ± 179.47

107.39 ± 96.47

269.50 ± 185.96

 < 0.001

B cells/TBNK, mean ± SD (%)

8.80 ± 5.10

9.41 ± 6.84

8.52 ± 4.07

0.601

B cells, n ± SD (cells/μl)

117.27 ± 92.39

67.36 ± 45.47

140.23 ± 99.36

 < 0.001

TBNK, n ± SD (cells/μl)

1371.39 ± 751.49

809.90 ± 443.86

1629.67 ± 723.69

 < 0.001

CD4/CD8 ratio, mean ± SD

1.15 ± 0.60

1.21 ± 0.61

1.12 ± 0.59

0.320

  1. Tested by Mann–Whitney U test
  2. HLA-DR human leukocyte antigen-DR, MFI median fluorescence intensity, SD standard deviation, TBNK T, B and NK cells, NK cells natural killer cells
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Journal of Translational Medicine

ISSN: 1479-5876

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