Skip to main content

Table 4 Summary of function and structure of the repurposed drugs for breast cancer

From: RepCOOL: computational drug repositioning via integrating heterogeneous biological networks

Rank

Repurposed drugs

Current usagesa

Structure

1

Doxorubicin

Treatment of leukemia, lymphoma, neuroblastoma, sarcoma, Wilms tumor, and cancers of the lung, breast, stomach, ovary, thyroid, and bladder

View full size image

2

Paclitaxel

Treatment of AIDS-related Kaposi sarcoma, advanced ovarian cancer, and certain types of breast cancer

View full size image

3

Tamoxifen

Treatment of the ovary, breast cancer, desmoid tumors and endometrial cancers

View full size image

  1. aAccording to National Institutes of Health (NIH) (https: 2019, June) and Drug bank (https 2019, June)