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TableĀ 4 Summary of function and structure of the repurposed drugs for breast cancer

From: RepCOOL: computational drug repositioning via integrating heterogeneous biological networks

Rank Repurposed drugs Current usagesa Structure
1 Doxorubicin Treatment of leukemia, lymphoma, neuroblastoma, sarcoma, Wilms tumor, and cancers of the lung, breast, stomach, ovary, thyroid, and bladder
2 Paclitaxel Treatment of AIDS-related Kaposi sarcoma, advanced ovarian cancer, and certain types of breast cancer
3 Tamoxifen Treatment of the ovary, breast cancer, desmoid tumors and endometrial cancers
  1. aAccording to National Institutes of Health (NIH) (https: 2019, June) and Drug bank (https 2019, June)