From: RepCOOL: computational drug repositioning via integrating heterogeneous biological networks
Rank | Repurposed drugs | Current usagesa | Structure |
---|---|---|---|
1 | Doxorubicin | Treatment of leukemia, lymphoma, neuroblastoma, sarcoma, Wilms tumor, and cancers of the lung, breast, stomach, ovary, thyroid, and bladder | |
2 | Paclitaxel | Treatment of AIDS-related Kaposi sarcoma, advanced ovarian cancer, and certain types of breast cancer | |
3 | Tamoxifen | Treatment of the ovary, breast cancer, desmoid tumors and endometrial cancers |