RepCOOL: computational drug repositioning via integrating heterogeneous biological networks

Table 1 Primary data sources for drug-disease network reconstruction

Network type	Source database	Network details	URL address	References
DRGN	Drug bank	No. of drugs: 1497 No. of genes: 673 No. of interactions: 3509	https://www.drugbank.ca/	[14]
DIGN	CTD	No. of diseases: 3158 No. of genes: 47,740 No. of interactions: 26,047,815	http://ctdbase.org/	[15]
DIGN	OMIM	No. of diseases: 4552 No. of genes: 6175 No. of interactions: 6666	https://www.omim.org/	[16]
DIGN	DisGeNET	No. of diseases: 20,371 No. of genes: 17,068 No. of interactions: 561,107	http://www.disgenet.org/	[17]
PPIN	Intact	No. of proteins: 16,523 No. of interactions: 143,758	https://www.ebi.ac.uk/intact/	[18]
GCN	COXPRESdb	No. of genes: 24,442 No. of interactions: 12,485	http://www.COXPRESdb.org/	[19]

ISSN: 1479-5876