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Fig.9 | Journal of Translational Medicine

Fig.9

From: Down-regulation of PADI2 prevents proliferation and epithelial-mesenchymal transition in ovarian cancer through inhibiting JAK2/STAT3 pathway in vitro and in vivo, alone or in combination with Olaparib

Fig.9

Downregulation of PADI2 combinated with Olaparib repressed the proliferation of tumor cells in vivo. a SKOV3 stable cell line was used to construct ovarian cancer subcutaneous xenograft model of nude mouse. The body weight of each mouse was measured every three days since the indicated treatments began. n = 5. b The nodules were lighter in SKOV3-shPADI2 combinated with Olaparib group compared with the control group. Quantification of tumors weight is on the right. c Tumors grew more slowly after transfection of PADI2 shRNA in vivo. Quantitative analyses of tumors growth. *P < 0.05, **P < 0.01, ***P < 0.001

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Journal of Translational Medicine

ISSN: 1479-5876

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