Skip to main content
Fig.7 | Journal of Translational Medicine

Fig.7

From: Down-regulation of PADI2 prevents proliferation and epithelial-mesenchymal transition in ovarian cancer through inhibiting JAK2/STAT3 pathway in vitro and in vivo, alone or in combination with Olaparib

Fig.7

Identification of differentially expressed genes (DEGs) in A2780-shPADI2 and SKOV3-shPADI2 cell by transcriptome sequencing analysis. a Clustering heatmap of the 22,618 and 22,995 genes exhibiting significantly differential expression, statistically significant DEGs were defined as |Log2 Fold change|> 2 and P value < 0.05 in A2780-shPADI2 and SKOV3-shPADI2 cell than A2780 and SKOV3 cell, respectively. b Volcano plot of the 22,618 and 22,995 expressed genes in A2780-shPADI2 and SKOV3-shPADI2 cell than A2780 and SKOV3 cell, respectively. Red color represented up-regulated genes in A2780-shPADI2 and SKOV3-shPADI2 cell than A2780 and SKOV3 cell and blue color represented down-regulated genes. All data are expressed from triplicate experiments

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us