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Fig.6 | Journal of Translational Medicine

Fig.6

From: Down-regulation of PADI2 prevents proliferation and epithelial-mesenchymal transition in ovarian cancer through inhibiting JAK2/STAT3 pathway in vitro and in vivo, alone or in combination with Olaparib

Fig.6

Downregulating PADI2 and Olaparib combination treatment suppresses the migration and invasion of A2780 and SKOV3 cells. a Wound-healing assay was performed in A2780 and SKOV3 cells(Scale bar 100 μm). b Cell migration and migrated number were showed by transwell assay in A2780 and SKOV3 cells after PADI2 knockdown with and without the treatment with Olaparib(Scale bar 25 μm). Quantitative analyses of migration and invasion abilities showed in the right side. All data are expressed as the mean ± SD of values from triplicate experiments. *P < 0.05, **P < 0.01 and ***P < 0.001 compared with control group

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