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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Lentiviral delivery of combinatorial CAR/CRISPRi circuit into human primary T cells is enhanced by TBK1/IKKɛ complex inhibitor BX795

Fig. 4

Cell growth rate and CD27/CD28 expression of transduced T cells. a T cell expansion rate on day 3, day 6, and day 10, with the absence or presence of BX795. RB-340-1F transduction was performed on day 1 and day 2 as described in method, including non-transduced (NT) group as a control. Cell sorting is not carried out in this experiment. Fold of expansion is calculated by dividing the actual cell number on designated day with the cell number counted on day 1. b Expression of CD27 and CD28 in RB-340-1F double transduced cells on day 6 and day 10. Experiments were done with more than three donors. Data presented is from one representative donor

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