Fig. 1

RB-340-1F two-vector platform and T cell transduction workflow. a Schematic representation of the first lentiviral vector LdCK-GFP and the second lentiviral vector CAR-TEV-mCherry. b The percentages of cells expressing the activation markers CD69, CD25, and cell surface protein LDLR. T cells were stimulated in anti-CD3/anti-CD28 pre-coated plate (CD3/CD28 activation). T cells cultured in non-coated plate were used as control (no activation). Results are the averages of two donors. c T cell transduction workflow and the time window to add BX795. The final concentration of BX795 in cell culture is 4 µM