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Table 5 Binary logistic regression analysis of clinicopathological characteristics of patients admitted who had COVID-19 PCR + (n = 122)

From: Prognostic factors in patients admitted to an urban teaching hospital with COVID-19 infection

 

Alive (n = 83)

Dead (n = 39)

p-value

O.R

95%CI

p-value

Age (< / ≥ 70 years)

53/30

12/27

 < 0.001

4.7

2.0–11.3

0.001

Sex (male/female)

39/44

16/23

0.219

   

BMI (< 20; ≥ 20–29; ≥ 30 kg/m2)

5/37/41

3/18/18

0.798

   

SIMD (1 (least)–6 (most) deprived)

9/1/16/10/21/37

4/0/9/6/2/21

0.959

   

Ethnicity (1–5)

79/0/3/1/0

37/0/0/0/2

0.441

   

Living circumstances (0–3)

72/8/2/1

30/0/7/2

0.027

   

Past Medical History

 Hypertension (y/n)

33/50

20/19

0.233

–

–

0.765

 Heart failure (y/n)

4/79

7/32

0.019

4.4

1.1–18.6

0.042

 T1DM (y/n)

1/82

0/39

0.493

   

 T2DM (y/n)

22/61

10/29

0.920

   

 Chronic renal failure (y/n)

9/74

8/31

0.152

   

 Cognitive impairment (y/n)

8/75

12/27

0.003

   

 Previous delirium (y/n)

3/80

10/28

 < 0.001

   

 Frailty score (≤ / > 3)

53/30

8/31

 < 0.001

   

 COPD (y/n)

11/72

11/28

0.046

–

–

0.279

 Smoker

41/35/7

16/22/1

0.833

   

 Alcohol excess (y/n)

5/78

5/34

0.204

   

 Liver disease (y/n)

6/77

2/37

0.663

   

 Hep C (never/previous/active)

82/0/1

39/0/0

0.493

   

 Active cancer (y/n)

4/79

1/38

0.560

   

Diagnostic criteria

 CXR negative/positive

38/45

22/16

0.218

   

Physiology at presentation

 NEWS (≤ / > 4)

36/46

10/29

0.054

─

─

0.146

 Delirium (y/n)

6/77

10/27

0.003

   

Laboratory results at presentation

 poGPS (0/1/2)

63/16/2

24/11/3

0.063

2.4

1.1–5.1

0.027

 NLR (< 3/ 3–5 / ≥ 5)

21/23/38

5/6/28

0.015

─

─

0.144

 Hb (≥ / < 12.0 g/dL)

65/17

28/10

0.497

   

 MCV (≤ / > 99 fl)

75/7

30/9

0.028

─

─

0.235

 Hct (male ≥ / < 0.40) (female ≥ / < 0.37) L/L

59/23

23/16

0.155

   

 Platelets (< 150/ ≥ 150- < 450/ ≥ 450 × 109)

14/67/0

9/30/1

0.452

   

 Sodium (≤ 133 /134 -145/ ≥ 146 mmol/L)

10/71/2

5/31/3

0.240

   

 Potassium (< 3.5/ ≥ 3.5 – ≤ 5.3/ > 53 mmol/L)

5/73/0

3/27/0

0.525

   

 Mg (≥ / < 0.75 mmol/L)

12/3

4/2

0.527

   

 Urea (≤ / > 7.0 mmol/L)

57/26

17/22

0.008

   

 Creatinine (≤ / > 130 umol/L)

76/7

34/5

0.450

   

 AST (≤ / > 40 IU)

48/26

21/28

0.466

   

 ALT (≤ / > 56 IU)

69/12

33/5

0.810

   

 ALP (≤ / > 150 IU)

75/6

37/1

0.304

   

 Bilirubin (≤ / > 17 mmol/L)

78/3

35/3

0.332

   

 Glucose (≤ / > 7 mmol/L)

40/27

18/12

0.978

   

 Lactate (< / ≥ 2 mmol/L)

24/6

13/7

0.241

   

 HCO3 (≥ / < 22 mmol/L)

16/4

9/3

0.744

   

 PT (≤ / > 13 s)

53/16

19/11

0.169

   

 APPT (≤ / > 38 s)

67/3

3/26

0.253

   
  1. Living circumstances: 0 = independent, 1 = sheltered accommodation, 2 = care home, 3 = nursing home
  2. Ethnicity: White = 1, Mixed = 2, Asian = 3, Black = 4, Other ethnic groups = 5
  3. poGPS peri-operative Glasgow prognostic score, NLR neutrophil lymphocyte ratio