Table 5 Binary logistic regression analysis of clinicopathological characteristics of patients admitted who had COVID-19 PCR + (n = 122)
From: Prognostic factors in patients admitted to an urban teaching hospital with COVID-19 infection
| Alive (n = 83) | Dead (n = 39) | p-value | O.R | 95%CI | p-value | |
|---|---|---|---|---|---|---|
| Age (< / ≥ 70 years) | 53/30 | 12/27 | < 0.001 | 4.7 | 2.0–11.3 | 0.001 |
| Sex (male/female) | 39/44 | 16/23 | 0.219 | |||
| BMI (< 20; ≥ 20–29; ≥ 30 kg/m2) | 5/37/41 | 3/18/18 | 0.798 | |||
| SIMD (1 (least)–6 (most) deprived) | 9/1/16/10/21/37 | 4/0/9/6/2/21 | 0.959 | |||
| Ethnicity (1–5) | 79/0/3/1/0 | 37/0/0/0/2 | 0.441 | |||
| Living circumstances (0–3) | 72/8/2/1 | 30/0/7/2 | 0.027 | |||
| Past Medical History | ||||||
| Hypertension (y/n) | 33/50 | 20/19 | 0.233 | – | – | 0.765 |
| Heart failure (y/n) | 4/79 | 7/32 | 0.019 | 4.4 | 1.1–18.6 | 0.042 |
| T1DM (y/n) | 1/82 | 0/39 | 0.493 | |||
| T2DM (y/n) | 22/61 | 10/29 | 0.920 | |||
| Chronic renal failure (y/n) | 9/74 | 8/31 | 0.152 | |||
| Cognitive impairment (y/n) | 8/75 | 12/27 | 0.003 | |||
| Previous delirium (y/n) | 3/80 | 10/28 | < 0.001 | |||
| Frailty score (≤ / > 3) | 53/30 | 8/31 | < 0.001 | |||
| COPD (y/n) | 11/72 | 11/28 | 0.046 | – | – | 0.279 |
| Smoker | 41/35/7 | 16/22/1 | 0.833 | |||
| Alcohol excess (y/n) | 5/78 | 5/34 | 0.204 | |||
| Liver disease (y/n) | 6/77 | 2/37 | 0.663 | |||
| Hep C (never/previous/active) | 82/0/1 | 39/0/0 | 0.493 | |||
| Active cancer (y/n) | 4/79 | 1/38 | 0.560 | |||
| Diagnostic criteria | ||||||
| CXR negative/positive | 38/45 | 22/16 | 0.218 | |||
| Physiology at presentation | ||||||
| NEWS (≤ / > 4) | 36/46 | 10/29 | 0.054 | ─ | ─ | 0.146 |
| Delirium (y/n) | 6/77 | 10/27 | 0.003 | |||
| Laboratory results at presentation | ||||||
| poGPS (0/1/2) | 63/16/2 | 24/11/3 | 0.063 | 2.4 | 1.1–5.1 | 0.027 |
| NLR (< 3/ 3–5 / ≥ 5) | 21/23/38 | 5/6/28 | 0.015 | ─ | ─ | 0.144 |
| Hb (≥ / < 12.0 g/dL) | 65/17 | 28/10 | 0.497 | |||
| MCV (≤ / > 99 fl) | 75/7 | 30/9 | 0.028 | ─ | ─ | 0.235 |
| Hct (male ≥ / < 0.40) (female ≥ / < 0.37) L/L | 59/23 | 23/16 | 0.155 | |||
| Platelets (< 150/ ≥ 150- < 450/ ≥ 450 × 109) | 14/67/0 | 9/30/1 | 0.452 | |||
| Sodium (≤ 133 /134 -145/ ≥ 146 mmol/L) | 10/71/2 | 5/31/3 | 0.240 | |||
| Potassium (< 3.5/ ≥ 3.5 – ≤ 5.3/ > 53 mmol/L) | 5/73/0 | 3/27/0 | 0.525 | |||
| Mg (≥ / < 0.75 mmol/L) | 12/3 | 4/2 | 0.527 | |||
| Urea (≤ / > 7.0 mmol/L) | 57/26 | 17/22 | 0.008 | |||
| Creatinine (≤ / > 130 umol/L) | 76/7 | 34/5 | 0.450 | |||
| AST (≤ / > 40 IU) | 48/26 | 21/28 | 0.466 | |||
| ALT (≤ / > 56 IU) | 69/12 | 33/5 | 0.810 | |||
| ALP (≤ / > 150 IU) | 75/6 | 37/1 | 0.304 | |||
| Bilirubin (≤ / > 17 mmol/L) | 78/3 | 35/3 | 0.332 | |||
| Glucose (≤ / > 7 mmol/L) | 40/27 | 18/12 | 0.978 | |||
| Lactate (< / ≥ 2 mmol/L) | 24/6 | 13/7 | 0.241 | |||
| HCO3 (≥ / < 22 mmol/L) | 16/4 | 9/3 | 0.744 | |||
| PT (≤ / > 13 s) | 53/16 | 19/11 | 0.169 | |||
| APPT (≤ / > 38 s) | 67/3 | 3/26 | 0.253 | |||