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Table 2 Epidemiological studies of whole cannabis and cannabis extracts for anxiety (part 2)

From: Cannabis, a cause for anxiety? A critical appraisal of the anxiogenic and anxiolytic properties

Study

Data Source

Number

Route of Administration

Outcome

Cuttler et al. 2016 [59]

Recruited via word-of-mouth and links on advertisements posted on various websites and in Washington State cannabis dispensaries

1418 participants

Inhaled- (joints, bong, pipe, vaporiser) – (M) 89.8%, (F) 88%

Oral- (M) 3.9%, (F) 7.9%

Concentrates- (M) 5.4%, (F) 3.1%

Topical- (M & F) 0.4%

Other- (M) 0.6%, (F) 0.73%

Male: 55.3%

Female: 57.2%

Reported feeling less anxious or fearful

Corroon et al. 2017 [53]

Recruited via social media

2774 participants

N/A

46% reported using cannabis as a substitute for prescription drugs

Piper et al. 2017 [54]

New England dispensary members

1513 participants

N/A

71.8% reduced medication prescribed for anxiety

Corroon et al. 2018 [55]

Recruited via social media.

2409 participants

N/A

Almost 62% of CBD users reported using CBD to treat a medical condition. The top three medical conditions were pain, anxiety, and depression

Feingold et al. 2018 [58]

Data was drawn from Waves 1 and 2 of the National Epidemiologic survey on Alcohol and Related

Conditions

3723 participants

N/A

Remission rates for non-users: 66.0%

Remission rates for users: 52.8%)

Cuttler et al. 2018 [57]

Data from the cannabis tracking app StrainprintTM

5085 tracking sessions

Inhalation (smoking, vaping, concentrates, dab bubbler, dab portable)

93.5% of sessions recorded decrease in anxiety