Fig. 3

Therapy efficiency of different anti-HER2 antibodies in vivo. a Tumor cells isolated from the peritoneum (ascites) of SK-BR-3 transplanted HTM and TM are indicated. b Single cells isolated from the lung were stained with anti-HER2 antibody and quantified by flow cytometry. Numbers of animals in each group are indicated in brackets. For statistical analyses Dunnett’s multiple comparisons test was applied and significances are displayed (*p < 0.05). HTM, humanized tumor mice; TM, tumor mice; Trast, trastuzumab; Pert, pertuzumab