Fig. 2From: Lactobacillus sakei suppresses collagen-induced arthritis and modulates the differentiation of T helper 17 cells and regulatory B cellsL. sakei increases the IL-10 level and reduces the Th17 population and IL-17 expression in human PBMCs. a Normal human PBMCs were cultured with an anti-CD3 antibody for 72 h and the resulting CD4+IL-17+ and CD4+CD25highFoxp3+ cells were enumerated. b IL-17 and IL-10 levels in culture supernatant measured by ELISA. c Normal human PBMCs were cultured in the presence of lipopolysaccharide for 72 h and the resulting CD19+IL-10+ cells were enumerated. Data are means ± standard deviations from three independent experiments (*P < 0.05, **P < 0.03, ***P < 0.01)Back to article page