Fig. 5

Pathological and genetic concordance of PDX tumors during the passages compared with matched parental patient tumors. a Representative images of H&E-stained and IHC-stained tumor samples from the patients with LUSC and PDX passages 0, 1, and 2. Brown indicates pan-cytokeratin-positive or CD105-positive staining. Scale bars, 200 μm. b Correlation analysis of transcriptome profiles between the patients with LUSC and PDX passages for SP_079 and SP_100 models