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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: C6-ceramide treatment inhibits the proangiogenic activity of multiple myeloma exosomes via the miR-29b/Akt pathway

Fig. 5

Inhibition of miR-29b on the expressions of Akt pathway in HUVECs. a The qPCR analysis showed the expressions of Akt3, PI3K and VEGFA in OPM2 after ExomiR-29b inhibitor treatment. b The qPCR showed the expressions of Akt3, PI3K and VEGFA in RPMI-8226 after ExomiR-29b inhibitor treatment. β-Actin is used as noiR-29b inhibitor treatment. c Western blots showed the expressions of Akt3, P-AKT, PI3K and VEGFA in OPM2 after ExomiR-29b inhibitor treatment. β-Actin is used as normalization control for the total lysate. d Western blots showed the expressions of Akt3, P-AKT, PI3K and VEGFA in RPMI-8226 after ExomiR-29b inhibitor treatment. β-Actin is used as normalization control for the total lysate. The experiments were performed in triplicates. The data shown were representatives of three independent experiments that gave similar results. (*P < 0.05)

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