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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Preconditioning with rHMGB1 ameliorates lung ischemia–reperfusion injury by inhibiting alveolar macrophage pyroptosis via the Keap1/Nrf2/HO-1 signaling pathway

Fig. 6

Keap1/Nrf2/HO-1 pathway inhibition can suppress the anti-oxidant effects of rHMGB1 preconditioning in LIRI. a ROS. b MDA. c 15-F2t-isoprostane. d SOD. e GSH-PX. f CAT. (*p < 0.05, compared to control group, #p < 0.05, compared to I/R group, ^p < 0.05, comparison between rHMGB1 + I/R and brusatol + rHMGB1 + I/R group)

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