Fig. 4

rHMGB1 preconditioning mediates the activity of the Keap1/Nrf2/HO-1 pathway in a mouse model of lung I/R. a Representative western blot images of nuclear Keap1 in lung tissues. b Nuclear Keap1 levels in lung tissues. c Representative western blot images of nuclear Nrf2 in lung tissues. d Nuclear Nrf2 expression levels in lung tissues. e Representative western blot images of cytosolic HO-1 in lung tissues. f Cytosolic HO-1 expression levels in lung tissues. (*p < 0.05, compared to control group, ^#p < 0.05, comparison between I/R and rHMGB1 + I/R group)