Fig. 1

rHMGB1 preconditioning ameliorates tissue damage, inflammatory response, and HMGB1 expression induced by lung I/R injury. a Morphological changes in control, rHMGB1, I/R, and rHMGB1+ I/R groups observed using H&E staining. Magnification, ×200. b Lung injury scoring. c Wet/dry ratios in lung tissues. d IL-1β abundance in lung tissues. e IL-6 abundance in lung tissues. f NF-κB abundance in lung tissues. g Representative western blot images of HMGB1 in nuclear protein. h HMGB1 abundance in nuclear protein. (*p < 0.05 vs control group, ^#p < 0.05 vs I/R and rHMGB1+ I/R group)