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Table 1 Univariate and multivariate cox analyses in gliomas in CGGA

From: Clinical characterization, genetic profiling, and immune infiltration of TOX in diffuse gliomas

Factor CGGA RNA-seq set
Univariate Multivariate
P HR 95% CI P HR 95% CI
TOX
 High vs. low < 0.001 2.34 1.95–2.82 < 0.001 1.44 1.18–1.76
Age
 Increasing years < 0.001 1.03 1.02–1.04 0.044 1.01 1.00–1.02
Gender
 Male vs. female 0.823 1.02 0.85–1.22 0.518 0.98 0.82–1.17
WHO grade
Grade III vs. II < 0.001 3.01 2.26–4.00 < 0.001 2.90 2.17–3.86
 Grade IV vs. II < 0.001 8.53 6.40–11.01 < 0.001 5.22 3.88–7.02
1p19q status
 Codel vs. non-codel < 0.001 4.41 3.26–5.97 < 0.001 2.56 1.85–3.55
IDH status
Mutation vs. wild-type < 0.001 3.12 2.59–3.75 0.023 1.23 0.99–1.54