Fig. 9From: Clinical characterization, genetic profiling, and immune infiltration of TOX in diffuse gliomasWorking model of the effect of TOX in the immune system of glioma. TOX is highly expressed in glioma, regulating B cell activation and suppressing NK cell mediated immunity and lymphocyte chemotaxis and migration. TOX also mediates T cell proliferation and T cell exhaustion, while suppressing T cell migration and cytokine productionBack to article page