Fig. 2
From: Clinical characterization, genetic profiling, and immune infiltration of TOX in diffuse gliomas
a TOX expression is upregulated in female patients with gliomas from CGGA. b The expression levels of TOX based on the histopathologic classification from CGGA. A, low-grade astrocytoma; AA, anaplastic astrocytoma; AO, anaplastic oligodendroglioma; GBM, glioblastoma; O, oligodendroglioma; rA, recurrent low-grade astrocytoma; rAA, recurrent anaplastic astrocytoma; rGBM, recurrent glioblastoma; rO, recurrent oligodendroglioma; sGBM, sensitive glioblastoma; AOA, anaplastic oligoastrocytoma; OA, oligoastrocytoma. c The TOX expression pattern in the TCGA molecular subtype in pan-glioma analysis and GBM samples. d TOX expression is detected in different anatomic locations for GBM in the IVY GBM database. LE (Leading Edge), IT (Infiltrating Tumour), CT (Cellular Tumour), PAN (Pseudopalisading Cells Around Necrosis), PNZ (Perinecrotic Zone), MVP (Microvascular Proliferation), and HBV (Hyperplastic Blood Vessels). e ROC curves predict that TOX is a biomarker of classical and mesenchymal subtype glioma. f TOX is more highly expressed in LGG than in GBM at the protein level