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Table 3 Anemia and thrombocytopenia in confirmed NEC

From: Erythropoietin prevents necrotizing enterocolitis in very preterm infants: a randomized controlled trial

 

Control

n = 35

rhEPO

n = 19

p-value

Total

n = 54

Days at diagnosis with NEC, d

12.6 ± 11.5

10.7 ± 11.3

0.555

11.9 ± 11.4

Gestational age at diagnosis with NEC, w

31.4 ± 1.9

31.5 ± 2.6

0.864

31.4 ± 2.1

Anemia before NEC, n/total (%)

24/35 (68.6%)

11/19 (57.9%)

0.553

35/54 (64.8%)

Hb < 90 g/l before NEC, n/total (%)

8/35 (22.9%)

4/19 (21.1%)

0.879

12/54 (22.2%)

RBC transfusion before NEC, n/total (%)

8/35 (22.9%)

6/19 (31.6%)

0.528

14/54 (25.9%)

Time between transfusion and NEC, hours

29.8 ± 68.0

49.8 ± 89.7

0.361

36.8 ± 76.1

Number of RBC transfusions

2.7 ± 1.0

1.2 ± 0.4

0.004

2.0 ± 1.1

Thrombocytopenia, n/total (%)

15/35 (42.9)

10/19 (52.6)

0.573

25/54 (46.3)

Platelet count (× 109/l)

135 ± 93

103 ± 73

0.204

123 ± 87