Fig. 5
From: A modular framework for the development of targeted Covid-19 blood transcript profiling panels
Changes in abundance of transcripts comprising aggregate A28 in response to SARS-CoV-2 infection. The heatmaps display the changes in transcript abundance in three Covid-19 patients comprising the Xiong et al. RNA-seq transcriptome dataset. The top heatmap summarizes the module-level values for the six modules forming aggregate A28. The color code indicates membership to one of the three Covid-19 module sets that were defined earlier. The bottom heatmap shows patterns of abundance for the same six modules, but at the individual gene level. The line graphs on the right show changes in abundance for three transcripts from the “therapeutic relevance panel” in three Covid-19 patients profiled by Ong et al. using a generic Nanostring immune set comprising 594 transcripts